Quote :

"she told me that a lot of their patients who are on generic medication complain that they gain weight when they switch from name brand to generic."

the fda gives generic manufacturers wayyyyyyy more leeway when it comes to drugs.

they test for lots of things, but they don't test for function. they should. just b/c it contains a generic version of the main ingredient, does not mean that it will work at all, as you have already found out.

I am rather reluctant to use generics now that I know how much (or lack of) testing is required.

If it's for something that matters (antibiotics, pain meds, etc...) pay extra for the name brand. If it's something trivial, like generic advil or tylenol, that's ok.

2/10/2011 9:28:50 PM

Quote :

"just b/c it contains a generic version of the main ingredient"

oh no no no!!!! any bio equivalent drugs are REQUIRED to have the exact same active ingredients in the exact same amounts. theres no such thing as "generic active ingredient"

but be careful, this doesnt mean brand name is better, just means the effects are better known!


the diluents can make a HUGE difference on absorption.
they are required to do xx number of tests but not at all strengths.

and also sometimes they only measure how much is absorbed rather than how much over time.

so if you have 250 mg of drug A that gets absorbed over a time of 5 hours vs
the generica brand that gets absorbed over a time of 2.
this means the peak concentration has a chance of being 2x as high as the previous!

its insane.

but this doesnt mean that brand name is always better, its dependent upon the peak and duration of absorption, some people may need only a 2 hour absorption window as opposed to a 5 hour one.




(this is my life yo! i love this shit )



[Edited on February 10, 2011 at 10:04 PM. Reason : gjhghgf]

2/10/2011 9:59:54 PM

I always wondered why generic benadryl or claritin didn't do shit for me even though the active ingredient dosage was the same....

2/10/2011 10:08:04 PM

i have the same issue with advil and klonopin.

the brand names dont do much for me at all.

ibuprofen and clonazepam all the way homies.

[Edited on February 10, 2011 at 10:10 PM. Reason : sdfds]

2/10/2011 10:10:08 PM

So I contacted Muscle Milk b/c I wanted to sample their new light flavors. Well I got this nice sample box for them. Awesome can't wait to try it.

2/11/2011 12:53:09 AM

thanks Joie it is great having a (future) pharmacist in here to explain this stuff.

ask me about side effects and initial drug testing and i got that on lock. but Joie knows how all this stuff actually works

2/11/2011 8:43:10 AM

awww thank you boo

the weird thing, i find myself able to answer questions friends and family ask without looking stuff up anymore
and i find myself very confident in the answers i give (even though ill look them up to double check)
and the other day i got one of my grandmas medications altered because it was interferring with her coumadin! (her blood was wayyyyyyy too thin, like 10-15x )
it makes me feel really good (not that her blood was thin, but that im able to catch it!)

2/11/2011 1:01:58 PM

OK, so where's everyone's progress pics / info?

I want to see some motivation, no excuses!

2/11/2011 3:24:52 PM

I posted mine (although no pics) on the last page. Cut me some slack. After 2 years of working out and dieting I'm finally losing weight. Trust me getting below 146 is HUGE for me because it means my cortisol levels are no longer fighting against my birth control and body weight. Pictures soon. When I get to 140

2/11/2011 3:54:16 PM

no worries

just trying to keep this thread going for the New Year's resolutioners

Eat right and don't skip your workouts! you'll get there!

2/11/2011 5:31:23 PM

wait hold up... iheartkisses is also lucyinthesky?!?!?!!

2/11/2011 5:33:54 PM

ill email you some photos h8r

2/11/2011 7:10:45 PM

I doubt I will be posting pictures any time soon, but in my first week I lost 2 inches at my waist and chest (both) and 3 pounds total. Monday we will see where I am with week 2.

2/12/2011 2:55:02 AM

12 miles complete in an hour and 59 minutes. Wohoo! I survived.

2/12/2011 1:23:49 PM

yay cass!!!

2/12/2011 2:41:03 PM

^^ Congrats. I probably would have died... and here I was all proud of myself for running Lake Johnson on a weekend

2/12/2011 2:53:02 PM

Thanks!!

No shame in running LJ on a weekend! Great job. And bravo for battling the horrid parking situation on a nice day.

2/12/2011 4:39:18 PM

dang you are a fast runner!!!

it takes me like forever to run that much. like 3 hours :/ my pace for the first 6-7 miles is always on target to finish in like 2:15 but then...i seriously can't keep it up for the second half of long runs.

good job!!!

2/12/2011 4:49:23 PM

Nice job, Cass!

I just ran 10.362 mi. at Umstead in 1:49:43, which is far from flat

I'm very proud!

Getting there!

2/12/2011 8:23:40 PM

last night i was at WillemJoel's wedding and had several people ask me if i had lost weight (which i have)
im not really trying to but it still is an awesome feeling

[Edited on February 13, 2011 at 7:45 AM. Reason : ()]

2/13/2011 7:44:54 AM

everyone always asks me if ive gained

2/13/2011 10:14:33 AM

^isn that what you want?

2/13/2011 10:18:24 AM

I had a few people ask me at the end of the summer last year if I've gained weight (actually they said my shoulders/arms looked bigger). I did a bit. Now I'm back down to 165

[Edited on February 13, 2011 at 11:03 AM. Reason : need food]

2/13/2011 11:02:42 AM

Am up to 215 miles so far and weighing in at 126 lbs this afternoon. Speed is up slightly. 5k pace is just below 21 minutes.

Feeling a lot stronger. Biggest difference is that I've switched from drinking one or two glasses of wine a night to drinking one glass of wind maybe once a week. The bf is very serious with his training, so he helps me stay in shape.

2/13/2011 7:47:49 PM

today,

hammer throws, jr. caber tossin, pushed and pulled jeep

tommorrow

chain squats, deads, calves (hah, no chains for these)

[Edited on February 13, 2011 at 8:21 PM. Reason : ]

2/13/2011 8:21:08 PM

I normally do my leg workout during the week about 7 hours after my lunch. I wasn't able to get to the gym much this week due to travel, so I went to the gym today for my leg workout about 2 hours after eating lunch. I was surprised at how much stronger I felt during my exercises. I was able to increase the poundage 10% on squats, and it still felt like I was doing my reps a lot faster.

I guess this means I need to start eating more carbs before my workouts. I occasionally eat a can of tuna or a bag of microwaveable pork rinds a few hours before my workouts when I'm at work, but I rarely have any carbs after lunch.

2/13/2011 8:32:58 PM

I wish this one early morning bitch would learn to eat her carbs before coming in. Last week, I had to buy her her 5th damn gatorade, due to her almost loosing consciousness. "OH, I don't know what's going on with my, my doctor has checked EVERYTHING!!!" "I feel fine after I have these gatorades!!"

"Do you eat breakfast or anything before you come in?'

"I have a zone bar!"

[Edited on February 13, 2011 at 8:38 PM. Reason : .]

2/13/2011 8:37:29 PM

so i think im gonna set a small goal. i wanna lose #10(ish)

i can do this. it would but me around 128ish.

i just gotta watch myself on the weekends!

2/13/2011 9:40:08 PM

I dreamed about having Bojangle's last night, except in my dream I focused on how greasy and salty it was. I remember seeing the grease drip off of it. It was weird.

2/14/2011 9:17:15 AM

Whoa Joie! Aren't you 5'9" or 5'10"? That would be uber tiny. Just be safe with it!

Granted, eating super clean and avoiding alcohol does make weight drop off pretty quickly. You're already in such good shape even with the occasional cheat day/wknd.

What are everyone's typical nutrition pitfalls? I'm a wine junkie, but have prob consumed just 10 drinks in the past month, as opposed to the 50 to 60 I'd typically consume. That's about a 5000 calorie difference right there. Kind of weird to think of it that way.

[Edited on February 14, 2011 at 10:09 AM. Reason : J]

2/14/2011 10:07:12 AM

But Joie's a model, I imagine her diet of cocaine and tic tacs would get her there pretty quickly



/completely kidding

ehee

2/14/2011 10:32:09 AM

Quote :

"It's for Paris, I'm on this new diet. Well, I don't eat anything and when I feel like I'm about to faint I eat a cube of cheese. I'm just one stomach flu away from my goal weight. "

- Emily, The Devil Wears Prada.

2/14/2011 10:46:46 AM

I've been keeping the same routine but it's my time of the month so progress has been uh up and down? hahaha I can't wait for it to be over so things will even out again.

2/14/2011 11:14:57 AM

did some serious damage this weekend.

i dont think i'm ever going to get anywhere if i keep up with the way i've been going on weekends.

ah well.

2/14/2011 11:17:47 AM

food? booze? both?

2/14/2011 11:19:24 AM

you didn't gain weight overnight, and you aren't gonna lose it overnight

one weekend off the horse isn't gonna kill all of your results, stick with it.

2/14/2011 11:27:11 AM

food and booze. see that the problem, it's been every weekend

gf had a bad day friday, so that turned into an ice cream/pizza/wine + movie then tequila then a case of beer between the two of us while playing darts.
then hangover pancakes and sausage, big italian dinner with friends with white wines, a couple rogue 22oz bottles, a six pack of breckenridge chocolate vanilla porters, then liquor drinks and things all night at the hoose
then hangover pancakes and sausage again, and a more respectable dinner/no drinks on sunday

planned rest days on friday seem to lead me to startin' partyin' way too early

did do 6mi hikes with the dogs both days (it was beautiful here this weekend) and some gym time. but still, whoa.

my goals are all super long term anyways. im not that concerned. just been going way overboard like, every single weekend.

2/14/2011 11:36:02 AM

Quote :

"Whoa Joie! Aren't you 5'9" or 5'10"? That would be uber tiny. Just be safe with it! "

i'm only about an inch or so taller than you (solid 5'9")

2/14/2011 11:36:42 AM

I didn't work out or run at all during the week last week because I was nursing a foot injury and a calf injury, but I did the Tour de Palm Springs century ride on Saturday, and it was great! 102 miles in 5:40 and felt pretty good doing it. Then my wife and I spent the rest of the weekend in Palm Springs and did a little hiking yesterday.

I'm a bit sore today, but at least I didn't reaggravate either of my injuries, so I'm gonna try and get back on the horse with running this week.

2/14/2011 12:08:07 PM

Quote :

"gf had a bad day friday, so that turned into an ice cream/pizza/wine + movie then tequila then a case of beer between the two of us while playing darts. then hangover pancakes and sausage, big italian dinner with friends with white wines, a couple rogue 22oz bottles, a six pack of breckenridge chocolate vanilla porters, then liquor drinks and things all night at the hoose then hangover pancakes and sausage again, and a more respectable dinner/no drinks on sunday"

Good god and I felt bad about my weekend. Did you two really drink a case (as in 24 beers) in one night? I haven't drank like that since my borderline-alky days in college.

My pitfalls are greasy food and beer/liquor. When I go out to a bar or club I always have a few drinks. I also usually start craving burgers/pizza/pasta at restaurants, but it gets easier to resist when I think about the calories and sodium in them. Haven't been eating out much lately either.

2/14/2011 1:52:50 PM

over the course of 8 hours or so, sure

2/14/2011 3:52:26 PM

so my start to 10 lb loss has began prettty shitty

ahahha

girl scout cookies came in todayate a few too many at lunch (along with my normal healthy stuff) but thats not the real issue. the problem lies in that i am SO DAMN TIRED.

this is the most lethargic i have been in a very very long time.

i was supposed to go meet someone at the gym to do bodypump and just called to cancel on them (to which their reply was "oh my gosh you REALLY are tired!)

but this feeling sucks because im eating more than usual, and im pretty sure its an effort to get energy.
it's a combo of healthy and non healthy

(ie i just had some grilled chicken and broccolli, and then a fudge round and 2 apples )
im eating A LOT more than i normally would


sighhh


welp, its only one day


and also, i thnk im gonna start going to the gym for a brief (like 20 minutes) session of cardio 2-4 mornings a week....ill let yall know how that goes

2/14/2011 4:41:08 PM

Well, now I have a foreseeable goal, my friend asked me to be her moh for a spring OR fall wedding next yr. Must be skinny!!!!!!!!!!!!!

2/14/2011 10:45:32 PM

just limit your calories and do something 5 or 6 days a week and you'll be there before you know it

2/15/2011 12:17:00 AM

I ran 3 miles yesterday and my knee started hurting really bad. I looked it up and it fits the symptoms for runner's knee to the "tee". FUUUUUUU

Basically rest, NSAIDS and stretching for the rest of the week. I was really hoping to put in some good miles this week.

2/15/2011 8:09:24 AM

Quote :

"girl scout cookies came in todayate a few too many at lunch"

hahaha. I ordered some a few weeks ago. I'm kind of hoping they just don't show up.

2/15/2011 8:24:58 AM

I refuse to order any though I'd love some! I just know I won't keep a steady slow pace with them ha

And dammit if the scale won't budge for the last 5 days! I'm doing everything the same and my muscles are sore, i'm hoping it's water retention and when that time is over it'll magically drop a few pounds, haha, and I hope it's before my official three week weigh in tomorrow...

2/15/2011 8:34:16 AM

w00t I'm done 4 pounds since the beginning of the month

Been doing nothing but running for exercise, plus I've cut down carbs by not eating rice, pasta, or pizza (except maybe once a week).

2/15/2011 8:40:39 AM

i guess i waited too long (damn procrastination) but the half marathon i was training for is officially sold out now. i was trying to run the Wrightsville Beach/Quintiles Half Marathon.

anyone know of any other half marathons in the Raleigh area I could look into?

2/15/2011 9:00:41 AM

Noen and I ran the VA Beach Rock N Roll Marathon a few years ago. It's Labor Day weekend each year. Flat, fast course and fun party weekend! Great race!

2/15/2011 9:03:54 AM